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Dictionary · Drug

ephedrine

A drug, given by IV injection, that raises blood pressure and heart rate.

eh-FED-rin nounHigh-alert drug

What it means

An adrenergic agonist given by IV injection, most often to treat low blood pressure caused by spinal or epidural anesthesia, including during labor. It acts on alpha and beta receptors and also makes nerve endings release norepinephrine, so it tightens blood vessels and makes the heart beat faster and harder. Its name looks and sounds like epinephrineep-ih-NEF-rinA hormone and drug, also called adrenaline, that raises heart rate and blood pressure and opens the airways.Full entry , and ISMP lists the two as names that get confused.

For the nurse

Check blood pressure and heart rate often after a dose, and in labor watch the fetal heart rate. Read the label carefully: ephedrine and epinephrine are not the same drug.

At a glance

Drug classadrenergic agonist (vasopressor)
Brand namesAkovaz, Corphedra, Emerphed
Spanishefedrina
Also writtenAkovaz, Corphedra, Emerphed

Easy to confuse with

epinephrine

A hormone and drug, also called adrenaline, that raises heart rate and blood pressure and opens the airways.

Related terms

hypotension

Blood pressure lower than normal, generally below 90/60 mm Hg in an adult.

epinephrine

A hormone and drug, also called adrenaline, that raises heart rate and blood pressure and opens the airways.

epidural anesthesia

Pain relief or numbness from an anesthetic drug given through a thin catheter into the space just outside the covering of the spinal cord.

norepinephrine

A hormone and nerve messenger that narrows blood vessels and raises blood pressure, also given as an IV drug.

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