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Dictionary · Drug

immunosuppressant

A drug that lowers the activity of the immune system.

im-yoo-noh-suh-PRES-unt noun

Word parts

immun/o immunesuppress hold down-ant agent

What it means

A medicine that weakens the body's immune response. It is used to stop the body rejecting a transplanted organ and to control autoimmune diseaseaw-toh-ih-MYOON dih-ZEEZA disease in which the immune system attacks the body's own healthy tissue.auto- selfimmune protectedFull entry such as rheumatoid arthritis, lupus and psoriasis. Examples include tacrolimus, cyclosporine, mycophenolate, azathioprine, methotrexate and corticosteroidkor-tih-koh-STER-oydA drug that acts like the hormones of the adrenal glands, used mainly to calm inflammation and the immune system.cortic/o cortex (the outer layer of the adrenal gland)-oid likeFull entry . The trade-off is a higher risk of infection and some cancers.

For the nurse

Give doses at the same times each day; levels of some, such as tacrolimus, are checked with blood tests. Teach infection prevention, to report fever or sore throat early, to avoid live vaccines and to protect the skin from the sun. Several of these drugs carry boxed warnings for serious infection and cancer.

At a glance

Drug classimmunosuppressant
Brand namesPrograf (tacrolimus); CellCept (mycophenolate)
Spanishinmunosupresor
Also writtenimmunosuppressive agent, immunosuppressants, immunosuppressive drug, immunosuppressive drugs

Related terms

corticosteroid

A drug that acts like the hormones of the adrenal glands, used mainly to calm inflammation and the immune system.

immune system

The body's defense system of cells, tissues and organs that fights germs and other foreign substances.

autoimmune disease

A disease in which the immune system attacks the body's own healthy tissue.

immunocompromised

Having an immune system that is weaker than normal at fighting infection.

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