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Dictionary · Drug

losartan

An angiotensin II receptor blocker (ARB) that lowers blood pressure and protects the kidneys.

loh-SAR-tan nounBoxed warning

What it means

A drug that blocks angiotensin II from tightening blood vessels and holding on to salt. It treats hypertensionhy-per-TEN-shunBlood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.hyper- above, more than normaltension pressureFull entry , protects the kidneys in type 2 diabetes and is used in heart failure. It works like an ACE inhibitor such as lisinoprilly-SIN-oh-prilAn ACE inhibitor drug that lowers blood pressure and protects the heart and kidneys.Full entry but rarely causes the dry cough. It can raise potassium and lower kidney function.

For the nurse

Check blood pressure, potassium and kidney function. Teach the client to rise slowly and that it must not be taken in pregnancy (boxed warning). Report swelling of the face or throat.

Remember it

"-sartan" drugs are ARBs.

At a glance

Drug classangiotensin II receptor blocker (antihypertensive)
Brand namesCozaar
Spanishlosartán
Also writtenCozaar

Easy to confuse with

simvastatin

A statin drug that lowers LDL cholesterol and the risk of heart disease.

Related terms

hyperkalemia

A blood potassium level above normal, over 5.0 mEq/L.

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

antihypertensive

A drug that lowers blood pressure.

lisinopril

An ACE inhibitor drug that lowers blood pressure and protects the heart and kidneys.

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