What it means
An HMG-CoA reductase inhibitor that lowers the liver's making of cholesterol. It is used for hyperlipidemiahy-per-lip-ih-DEE-mee-uhHigher than healthy levels of fats (lipids), such as cholesterol or triglycerides, in the blood.hyper- abovelip/o fat-emia in the bloodFull entry and to prevent heart attack and stroke. It is usually taken in the evening. Muscle pain is the main side effect; the risk of serious muscle injury is higher at the highest dose and with some drugs and grapefruit juice.
For the nurse
Teach the client to take it in the evening, avoid large amounts of grapefruit juice, and report unexplained muscle pain, weakness or dark urine. Tell the provider about a pregnancy or plans for one, since statins are usually stopped during pregnancy.
At a glance
| Drug class | antilipemic (HMG-CoA reductase inhibitor, statin) |
|---|---|
| Brand names | Zocor, FloLipid |
| Spanish | simvastatina |
| Also written | Zocor, FloLipid |
Easy to confuse with
losartan
An angiotensin II receptor blocker (ARB) that lowers blood pressure and protects the kidneys.
cetirizine
A second-generation antihistamine used for allergy symptoms and hives.
Related terms
atherosclerosis
A buildup of fatty deposits (plaque) inside the walls of the arteries.
hyperlipidemia
Higher than healthy levels of fats (lipids), such as cholesterol or triglycerides, in the blood.
atorvastatin
A statin drug that lowers LDL cholesterol and the risk of heart attack and stroke.