What it means
Progesterone keeps the lining of the uterus in place during pregnancy. By blocking it, mifepristone (Mifeprex) is used with misoprostolmy-soh-PROS-tolA prostaglandin drug that protects the stomach lining and also makes the cervix soften and the uterus contract.Full entry for medication abortion in early pregnancy and for managing early pregnancy loss. A different product (Korlym) treats high blood glucose in Cushing syndrome. Cramping and bleeding are expected after use for pregnancy.
For the nurse
Teach the client what bleeding and cramping to expect, and to seek care right away for very heavy bleeding (soaking two thick pads an hour for two hours in a row), fever lasting more than a day, or severe belly pain. It is dispensed under an FDA REMS program.
At a glance
| Drug class | progesterone receptor antagonist |
|---|---|
| Brand names | Mifeprex, Korlym |
| Also written | Mifeprex, Korlym |
Related terms
REMS
Risk Evaluation and Mitigation Strategy: an FDA-required safety program for certain drugs with serious risks.
misoprostol
A prostaglandin drug that protects the stomach lining and also makes the cervix soften and the uterus contract.