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Dictionary · Drug

misoprostol

A prostaglandin drug that protects the stomach lining and also makes the cervix soften and the uterus contract.

my-soh-PROS-tol nounBoxed warning

What it means

A man-made form of prostaglandin E1. It was first used to prevent stomach ulcers in people taking NSAIDs. In maternity care it is used to soften (ripen) the cervix before induction of labor, to treat heavy bleeding after birth, and with mifepristonemif-eh-PRIS-toneA drug that blocks the hormone progesterone, used with misoprostol to end an early pregnancy, and for some hormone disorders.Full entry to end an early pregnancy. Common side effects are diarrhea and belly cramps; fever and chills can follow higher doses.

For the nurse

When used for ulcer prevention, people who can become pregnant must not be pregnant and should use birth control, since it can cause miscarriage. During labor induction, watch contractions and the fetal heart rate closely for too-frequent contractions.

At a glance

Drug classprostaglandin E1 analog
Brand namesCytotec
Spanishmisoprostol
Also writtenCytotec

Related terms

ulcer

An open sore where the skin or the lining of an organ has broken down.

nonsteroidal anti-inflammatory drug

A drug that relieves pain, fever and inflammation and is not a steroid, such as ibuprofen or naproxen.

mifepristone

A drug that blocks the hormone progesterone, used with misoprostol to end an early pregnancy, and for some hormone disorders.

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