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nifedipine

A calcium channel blocker taken by mouth that relaxes blood vessels to lower blood pressure.

ny-FED-ih-peen noun

What it means

A dihydropyridine calcium channel blocker: it widens arteries but has little effect on the heart's conduction. Long-acting tablets treat high blood pressure and angina. In maternity care it is used for severe high blood pressure in pregnancy and to slow preterm labor. Side effects include headache, flushing, dizziness, a fast pulse and ankle swelling.

For the nurse

Extended-release tablets are swallowed whole. Check blood pressure and pulse, teach the client to rise slowly and avoid grapefruit juice. The fast-acting capsule is not used to bring down high blood pressure quickly, because the drop can be too sudden.

At a glance

Drug classcalcium channel blocker (dihydropyridine)
Brand namesProcardia XL, Adalat CC
Spanishnifedipino
Also writtenProcardia, Procardia XL, Adalat CC

Easy to confuse with

nicardipine

A calcium channel blocker, most often given as an IV infusion, that relaxes blood vessels to lower blood pressure.

Related terms

hypertension

Blood pressure that stays higher than normal, at or above 130/80 mm Hg by current US guidelines.

verapamil

A calcium channel blocker that slows the heart rate and relaxes blood vessels.

labetalol

A drug that blocks both alpha and beta receptors to lower blood pressure, given IV or by mouth.

nicardipine

A calcium channel blocker, most often given as an IV infusion, that relaxes blood vessels to lower blood pressure.

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