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total iron-binding capacity

A blood test that measures how much iron the blood's carrier protein, transferrin, could hold.

TOE-tul EYE-ern BYND-ing kuh-PAS-ih-tee noun

What it means

Iron travels in the blood bound to transferrin. TIBC shows how much transferrin there is to carry iron. When iron stores are low, the body makes more transferrin, so the TIBC goes up; in iron overload and in anemia of chronic disease it tends to be low. It is read with the serum ironSEER-um EYE-ernA blood test that measures the amount of iron carried in the blood.Full entry and ferritin.

At a glance

Normal rangeAbout 250–450 mcg/dL [45–80 µmol/L]; ranges vary by lab.
Also writtenTIBC

Related terms

anemia

A lower than normal number of red blood cells or amount of hemoglobin in the blood.

ferritin

A protein that stores iron in the body; its blood level shows how much iron is stored.

serum iron

A blood test that measures the amount of iron carried in the blood.

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