What it means
An antifibrinolytic. It is often called TXA, a short form ISMP lists as error-prone because it has been read as TPA (a clot-dissolving drug), so the full name is written in orders. Given IV, it is used for severe bleeding after trauma and after childbirth (best within 3 hours), and during some surgery. By mouth it treats heavy menstrual bleeding. Because it helps clots last, it is used carefully in people at risk of blood clots. ISMP lists tranexamic acid injection as a high-alert medication, because it has been given into the spine by mistake.
For the nurse
Check the label and route carefully: it is given IV or by mouth, never into the spinal or epidural space. Give IV doses slowly, as ordered, and teach the client to report signs of a clot, such as leg swelling or pain, chest pain or sudden shortness of breath.
At a glance
| Drug class | antifibrinolytic |
|---|---|
| Brand names | Cyklokapron, Lysteda |
| Spanish | ácido tranexámico |
| Also written | Cyklokapron, Lysteda |
Related terms
hemorrhage
A large loss of blood from a blood vessel, inside the body or out of it.
postpartum hemorrhage
Heavy bleeding after birth: a total blood loss of 1,000 mL or more, or blood loss with signs of low blood volume, within 24 hours.
trauma
A physical injury to the body, or a deeply distressing event and the emotional harm it leaves.
menorrhagia
Menstrual periods that are very heavy or last longer than usual.
TXA
An abbreviation for tranexamic acid, a drug that slows the breakdown of blood clots; ISMP advises writing the full name.