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excretion

The removal of wastes, or of a drug and its breakdown products, from the body.

ek-SKREE-shun noun

What it means

The way the body gets rid of what it does not need. Waste leaves mainly in urine and stool, and also through the lungs and sweat. In pharmacology, excretion is the last step of how the body handles a drug, after absorption, distribution and metabolism. Most drugs leave through the kidneys, so poor kidney function lets them build up.

For the nurse

Check kidney function (creatinine, urine output) before giving drugs cleared by the kidneys; the dose may need to be lowered.

At a glance

Spanishexcreción

Easy to confuse with

secretion

A substance a gland or cell makes and releases, such as mucus, saliva, sweat or a hormone.

Related terms

renal

Relating to the kidneys.

creatinine

A waste product of muscle that the kidneys remove from the blood; its blood level is used to measure how well the kidneys work.

toxicity

The harm a substance does to the body, or a state in which a drug has built up to a harmful level.

absorption

The taking in of a substance, such as a drug or a nutrient, into the bloodstream.

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